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MRT 68601 hydrochloride

Cat No.:

LIA037

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Chemical Name:

N-[3-[[5-Cyclopropyl-2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide hydrochloride

Chemical Structure：

Description of MRT 68601 hydrochloride

Potent TBK inhibitor

Product Information of MRT 68601 hydrochloride

Purity

≥98% (HPLC)

Molecular Weight

487.04

Formula

C25H34N6O2.HCl

CAS Number

1962928-25-1

PubChem ID

121513855

Pack Size

10 mg

InChI Key

BOBHGYDEKISHIZ-UHFFFAOYSA-N

Smiles

O=C(C1CCC1)NCCCNC2=C(C3CC3)C=NC(NC4=CC=C(N5CCOCC5)C=C4)=N2.Cl

Biological Activity

MRT 68601 hydrochloride is a potent TBK1 (TANK-binding kinase-1) inhibitor (IC₅₀ = 6 nM). Inhibits the formation of autophagosomes in lung cancer cells.

Storage

Store at room temperature.

For research use only, not intended for any clinical use.